Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Bronchoscopy-guided antimicrobial therapy for cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2024
- Jain K
[Cystic fibrosis carrier screening: a Health technology assessment.].
HTA - Health Technology Assessment Report
Details- 2024
- Colombo C
The effect of discontinuing hypertonic saline or dornase alfa on mucociliary clearance in elexacaftor/tezacaftor/ivacaftor treated people with cystic fibrosis: The SIMPLIFY-MCC Study.
primary studies published RCT
Details- 2024
- Donaldson SH
Point of care lung ultrasound in preschool children with cystic fibrosis: a case-controlled, prospective, pilot study.
primary studies published, non RCT
Details- 2024
- Crispino AA
Long-term therapy with CFTR modulators consistently improves glucose metabolism in adolescents and adults with cystic fibrosis.
primary studies published, non RCT
Details- 2024
- Cohen A
Long-term outcomes of early exposure to repeated general anaesthesia in children with cystic fibrosis (CF-GAIN): a multicentre, open-label, randomised controlled phase 4 trial.
primary studies published, non RCT
Details- 2024
- Wainwright CE
Clinical Trial to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/Nesolicaftor in Adults With CF - PHASE2 - RECRUITING
ongoing trials trial from www.clinicaltrials.gov
Details- 2024
- Kors van der Ent