Welcome in CFDB (Cystic Fibrosis DataBase)!
This is a web-based, free access tool for health care professionals, researchers and students to evaluate in real time what are the current evidences about clinical efficacy of interventions in CF.
You'll find more than 1,300 studies divided in 8 sections, including Cochrane reviews, Cochrane protocols, DARE, HTA and Economic reviews, published RCT, published non-RCT, congress abstracts and ongoing trials.
Objective of CFDB (Cystic Fibrosis DataBase)
CFDB is a database and was ideated to classify clinical studies to get answers to specific questions:
- which interventions are effective, in which groups of CF patients and for which outcomes?
- to what extent do the results of the literature allow to make decisions for specific clinical issues? What issues need to be studied further?
This tool may help clinicians, researchers, students to have a faster updated view of clinical research in CF by using queries on the main topics in CF care. It could also be helpful to anyone going to design new studies, as it provides a concise description of what is currently known and what issues, on the contrast, need additional research.
Latest articles
Bronchoscopy-guided antimicrobial therapy for cystic fibrosis
Cochrane Database of Systematic Reviews - Cochrane Review
Details- 2024
- Jain K
[Cystic fibrosis carrier screening: a Health technology assessment.].
HTA - Health Technology Assessment Report
Details- 2024
- Colombo C
Impact of Discontinuing Both Hypertonic Saline and Dornase Alfa after Elexacaftor-Tezacaftor-Ivacaftor in Cystic Fibrosis.
primary studies published RCT
Details- 2024
- Mayer-Hamblett N
The intermittent intrapulmonary deflation technique for airway clearance in patients with cystic fibrosis: A randomized trial.
primary studies published RCT
Details- 2024
- de Macedo JRFF
ACT with CF: A randomized trial of acceptance and commitment therapy vs supportive psychotherapy for adults with cystic fibrosis.
primary studies published RCT
Details- 2024
- O'Hayer CV
Coping and learning to Manage Stress with cystic fibrosis (CALM): A multisite telehealth randomized controlled trial to reduce depression and anxiety symptoms in adults with cystic fibrosis.
primary studies published RCT
Details- 2024
- Bathgate CJ
Successful Therapy over 12 Months of People with Cystic Fibrosis with Rare Non-phe508del Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mutations with Elexacaftor/Tezacaftor/Ivacaftor (ETI).
primary studies published, non RCT
Details- 2024
- Sütering T